Jigoku Sensei Nube is a Japanese anime series based on the manga of the same name. It follows the story of Meisuke Nueno, a teacher who possesses a demon's hand, which he uses to protect his students from supernatural threats. The series combines elements of horror, comedy, and drama, as Nube faces various spirits and demons while teaching at the school. The blend of supernatural and school life provides a unique and entertaining narrative.