Kimi no Koto ga Dai Dai Dai Dai Daisuki na 100-nin no Kanojo is a romantic comedy anime and manga series that follows the story of Rentarou Aijou, a high school student who is destined to meet 100 soulmates. After a series of failed romantic pursuits, he encounters a deity who reveals this extraordinary fate. The series humorously explores Rentarou's attempts to juggle multiple relationships, each filled with unique challenges and comedic situations.