Tsugumomo is an anime series that follows the life of Kazuya Kagami, a high school student who encounters a tsukumogami, a spirit that resides in objects. The spirit, Kiriha, takes the form of a young girl and begins to live with Kazuya, leading to various adventures and battles with other spirits. The series combines elements of supernatural action, comedy, and romance, offering a unique take on the interactions between humans and spirits.