Galilei Donna is an original anime series produced by A-1 Pictures, directed by Yasuomi Umetsu. The story follows the descendants of Galileo Galilei, three sisters who become targets due to their ancestor's mysterious inheritance, known as the Galileo Tesoro. As they embark on a journey to uncover the secrets of their lineage, they face numerous challenges and adversaries. The series combines elements of adventure, science fiction, and family dynamics.