Henrietta is a central character in the anime series Gunslinger Girl. She is a young girl who has been transformed into a cyborg by a secretive government agency known as the Social Welfare Agency. As a 'fratello,' she is paired with her handler, Giuseppe, and trained to carry out dangerous missions against terrorists and criminals. Henrietta struggles with the remnants of her human emotions and memories, creating a poignant contrast between her innocent appearance and her deadly abilities. Her character explores themes of identity, loyalty, and the loss of childhood innocence in a harsh, adult world.