Tsunade Senju is one of the legendary Sannin and the Fifth Hokage of Konohagakure in the anime series Naruto. A descendant of the Senju and Uzumaki clans, she is renowned for her unparalleled medical ninja skills and immense physical strength. Tsunade plays a crucial role in leading and protecting the village, particularly during the Fourth Shinobi World War. Her leadership is marked by her dedication to her comrades and her desire to preserve peace in the ninja world. Despite her tough demeanor, she deeply cares for her friends and the village's well-being.