Takagi-san is the main female protagonist in the anime series 'Karakai Jouzu no Takagi-san'. She is a middle school student known for her playful and teasing nature. Her primary target is her classmate and desk neighbor, Nishikata, whom she frequently teases in clever and humorous ways. Despite her teasing, Takagi-san harbors deep feelings for Nishikata, and her antics often hint at her affection. The series revolves around their lighthearted interactions, showcasing how Takagi-san's wit and charm lead to endearing moments between the two characters.