The Stone Mask is a pivotal artifact in the anime series 'JoJo no Kimyou na Bouken' (JoJo's Bizarre Adventure). It is an ancient Aztec mask that transforms humans into powerful vampires upon contact with blood. The mask serves as a catalyst for the series' initial events, setting the stage for the Joestar family's ongoing battle against supernatural forces. Its ability to grant immense power and immortality makes it a sought-after object, driving the narrative and character motivations throughout the series.