Cerebella is a playable character in Skullgirls, serving as a member of the Medici Mafia and a loyal enforcer for the organization. She is a flamboyant, acrobatic strongwoman who fights using her living hat, Vice-Versa, which transforms into massive arms and weapons. Her personality is energetic, theatrical, and fiercely devoted, especially to her boss, Lorenzo Medici. In the story, she is both a combatant and a key figure tied to the Medici family's criminal influence.