Thomas Anderson, known by his hacker alias Neo, is the protagonist of The Matrix series. Initially a computer programmer, Neo discovers the truth about the Matrix, a simulated reality created by sentient machines to subdue the human population. He is prophesied to be 'The One' who will bring an end to the war between humans and machines. Neo's journey involves mastering his abilities within the Matrix and leading the rebellion against the oppressive system, embodying themes of self-discovery and freedom.