Aya Akagami is a significant character in the anime series 'Mononoke.' She is the Lady of the House in the 'Bakeneko' arc, where her tragic past and mysterious circumstances are central to the story. Aya is depicted as a composed and enigmatic woman whose suffering and strength play a crucial role in the unfolding mysteries. Her character drives much of the emotional depth in her arc, as the Medicine Seller works to uncover the truth behind the haunting events.